Do you get the same error when using any of the following examples which does the same job?UPDATE ApplicationSettingsSET SettingValue = 'test1'WHERE SettingKey IN ('ServiceEmail', 'MapEmail', 'TestEmail', 'SupportEmail')UPDATE ApplicationSettingsSET SettingValue = 'test1'WHERE SettingKey = 'ServiceEmail' OR SettingKey = 'MapEmail' OR SettingKey = 'TestEmail' OR SettingKey = 'SupportEmail'Are you using ADO and Command Object to execute the queries? Post the VB code too.Peter LarssonHelsingborg, Sweden